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Figure 1 | Virology Journal

Figure 1

From: Cellular apoptosis induced by replication of hepatitis B virus: possible link between viral genotype and clinical outcome

Figure 1

Flow cytometry analysis of apoptotic effect by HBV genome A, B, and C. HepG2 cells were transiently transfected with HBV genome A, B, and C and incubated for 24 h (panel C, D, E, respectively) and 48 h (panel F, G, H, respectively) before collected and applied to FACS assay. Cells transfected with empty vector pcDNA3.1 (panel A) and cells treated with cisplatin (panel B) were used as (-) and (+) controls. Cells were labeled by annexin-V-Fitc (FL1-H) and propidium iodide (FL2-H). In each panel, the lower right square (LR) indicates the number of apoptotic cells' portion. Data: LR: A:0.62%, B: 17.32%, C: 2.53%, D: 2.69%, E:1.61%; F: 9.18%, G: 16.13%, H: 6.86%

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Virology Journal

ISSN: 1743-422X