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Figure 4 | Virology Journal

Figure 4

From: Porcine reproductive and respiratory syndrome virus (PRRSV) infection spreads by cell-to-cell transfer in cultured MARC-145 cells, is dependent on an intact cytoskeleton, and is suppressed by drug-targeting of cell permissiveness to virus infection

Figure 4

Confocal microscopy of FA-stained MARC-145 cells during PRRSV infection. A. IFN-γ pretreatment, 46 h p.i., arrows indicate several PRRSV-positive clusters, 50 μm; B. AK-2 + IFN-γ post-treatment, arrow indicates a single PRRSV-positive cell, 46 h p.i., 50 μm; C. AK-2 pretreatment, 42 h p.i., occasional PRRSV-positive cells (arrows), 50 μm; D. IFN-γ pretreatment, 50 μm; E. 45 h p.i. with PRRSV, 100 μm; F. Simultaneous AK-2 treatment and PRRSV infection, 45 h p.i., 100 μm. (Length of scale bar is indicated for each panel)

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