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Table 2 HSV-2 specific responses in the CD4 and CD8 cell populations. Number of ELISPOTs per 500,000 original PBMCs measured in samples depleted of either CD8 cells (designated CD4 cells) or depleted of CD4 cells (designated as CD8 cells) stimulated with various peptide pools in the IFN-γ ELISPOT assay. The peptide pools are described in Table 1 and the 1X dose of peptide is approximately 0.33 ug/ml of each individual peptide within the pool and the 10X dose is approximately 3.3 ug/ml of each peptide within the different pools. Control peptide is a single negative peptide. Sample was from subject 3.

From: Characterization of the IFN-γ T-cell responses to immediate early antigens in humans with genital herpes

  CD4 cells CD8 cells
Peptide pools 1X dose 10X dose 1X dose 10X dose
ICP27 all 15 2 0 0
ICP22 all 0 3 0 1
ICP0–1 0 2 0 0
ICP0–2 34 6 0 0
ICP0–3 6 0 0 1
ICP4–1/2 3 0 0 0
ICP4–3/4 45 26 0 43
ICP4–5/6 35 14 0 128
VP22 89 5 0 6
gD 47 25 0 0
Control peptide 0 0 0 0