Figure 2

FPS is more effective than FP or Sal alone in reducing viral exacerbation of asthma. Mice were sensitized with OVA and infected with RSV as described in Methods. From days 21 to 27 mice were treated daily with FP, Sal or FPS. On day 28, they were reinfected with RSV and then challenged with OVA. AHR was measured on day 29 (A). On day 30 the mice were sacrificed and a BAL cell differential was performed for macrophages (mac), eosinophils (eos), neutrophils (neut) and lymphocytes (lym) (B). H & E stained lung sections were examined for histopathology (C). Results are from one representative experiment of two performed.