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Table 2 Results of the three PCRs for the diagnosis of suspected CMV infections in comparison to pp65 antigenemia (gold standard)a.

From: Evaluation of three Polymerase chain reaction tests targeting morphological transforming region II, UL-83 gene and glycoprotein O gene for the detection of Human Cytomegalovirus genome in clinical specimens of immunocompromised patients in Chennai, India

Diagnostic test result pp65 Positives (n = 48) pp65 Negatives (n = 44)
  No. of Clinical specimens SENS (%) PPV (%) FN (%) No. of Clinical specimens SPEC (%) NPV (%) FP (%)
PCR for mtrII positive 48 100 87 0 7 84 100 14
PCR for mtr II negative 0     37    
PCR for UL 83 positive 27 56 87 44 4 91 66 8
PCR for UL 83 negative 21     40    
PCR for gO positive 21 44 91 56 2 95 61 4
PCR for gO negative 27     42    
  1. aAbbreviations: SENS, sensitivity; PPV, Positive predictive value; FN, False negative; SPEC, specificity; NPV, Negative predictive value; FP, False positive