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Table 2 Results of the three PCRs for the diagnosis of suspected CMV infections in comparison to pp65 antigenemia (gold standard)a.

From: Evaluation of three Polymerase chain reaction tests targeting morphological transforming region II, UL-83 gene and glycoprotein O gene for the detection of Human Cytomegalovirus genome in clinical specimens of immunocompromised patients in Chennai, India

Diagnostic test result

pp65 Positives (n = 48)

pp65 Negatives (n = 44)

 

No. of Clinical specimens

SENS (%)

PPV (%)

FN (%)

No. of Clinical specimens

SPEC (%)

NPV (%)

FP (%)

PCR for mtrII positive

48

100

87

0

7

84

100

14

PCR for mtr II negative

0

   

37

   

PCR for UL 83 positive

27

56

87

44

4

91

66

8

PCR for UL 83 negative

21

   

40

   

PCR for gO positive

21

44

91

56

2

95

61

4

PCR for gO negative

27

   

42

   
  1. aAbbreviations: SENS, sensitivity; PPV, Positive predictive value; FN, False negative; SPEC, specificity; NPV, Negative predictive value; FP, False positive
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Virology Journal

ISSN: 1743-422X