Table 1 Viral progeny recovered from superinfected cells. HEL cells containing or lacking quiescent KM110-R (MOI 6) were superinfected on day 4 with either KOS or n212 (MOIs of 10 and 30 respectively). Progeny virus harvested 18 hours later was then titrated on U2OS cells in the presence of HMBA (Methods).
From: Functional inaccessibility of quiescent herpes simplex virus genomes
Superinfecting virus | KM110-R | RFP- titre (PFU/mL) | RFP+ titre (PFU/mL) |
|---|---|---|---|
none | - | 0 | N/A |
|  | + | 0 | 1.25 × 103 ± 1.5 × 103 |
n212 | - | 3.66 × 107 ± 1.3 × 107 | N/A |
|  | + | 1.79 × 107 ± 8.6 × 106 | 1.00 × 104 ± 6.8 × 103 |
KOS | - | 5.52 × 107 ± 2.2 × 107 | N/A |
|  | + | 2.63 × 107 ± 3.9 × 106 | 8.30 × 106 ± 7.4 × 105 |