Table 3 Comparison of encoded amino acids (AA) from clones described here (top) with other SIV molecular clones (bottom). The number (#) and percent (%) changes (Δ) in the indicated regions of Env and Nef are given.
From: Development and characterization of positively selected brain-adapted SIV
Clone | Monkey | Derived From | #AA Δ in gp120 | #AA Δ in gp41 | #AA Δ in Nef | Δ consensus in Env & Nef |
|---|---|---|---|---|---|---|
108 | 225 | Viral RNA from Microglia supernatant | 0 | 1 | 0 | 0.08% |
109 | 225 | Viral RNA from Microglia supernatant | 1 | 0 | 0 | 0.08% |
122 | 225 | Viral RNA from Microglia supernatant | 0 | 0 | 0 | 0.00% |
129 | 225 | Viral RNA from Microglia supernatant | 1 | 1 | 0 | 0.17% |
141 | 225 | Viral RNA from Microglia supernatant | 1 | 2 | 1 | 0.35% |
142 | 225 | Viral RNA from Microglia supernatant | 1 | 0 | 1 | 0.17% |
153 | 321 | Viral RNA from Microglia supernatant | 1 | 3 | 2 | 0.52% |
159 | 321 | Viral RNA from Microglia supernatant | 0 | 2 | 2 | 0.35% |
169 | 321 | Viral RNA from Microglia supernatant | 0 | 2 | 1 | 0.26% |
SIVmac1A11 | 251-79 | Proviral DNA from Tissue culture cells | 28 | 8* | 18 | 4.72% |
SIVmac32H (pJ5) | 32H | Proviral DNA from Tissue culture cells | 24 | 14 | 19 | 4.98% |
SIVmac316 | 316-85 | Proviral DNA from Tissue culture cells | 19 | 8* | N/A | 3.07%** |
SIV/17E-Fr | 17E | Proviral DNA from Brain & Macrophages | 22 | 11* | 20 | 4.63% |
SIVmac239 | 239-82 | Proviral DNA from Tissue culture cells | 18 | 14 | 15 | 4.11% |