Skip to main content
Figure 3 | Virology Journal

Figure 3

From: The YXXΦ motif within the severe acute respiratory syndrome coronavirus (SARS-CoV) 3a protein is crucial for its intracellular transport

Figure 3

The ∆YXXΦ mutant localizes to the Golgi compartment. (A) Expression constructs for wild type 3a or its mutants were cotransfected with DsRed-ER or YFP-Golgi markers in Huh7 cells, followed by staining with anti-3a antibodies. (B) Quantitative estimates of subcellular distribution patterns of the 3a and its mutants. Golgi saturated and plasma membrane distribution pattern was quantified by looking at colocalisation with Golgi marker and surface staining respectively. A total of at least 50 different expressing cells were analyzed for each condition. Data shown are representative of three different experiments.

Back to article page

Virology Journal

ISSN: 1743-422X