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Table 3 Biochemical response results

From: Efficacy and resistance in de novo combination lamivudine and adefovir dipivoxil therapy versus entecavir monotherapy for the treatment-naive patients with chronic hepatitis B: a meta-analysis

Follow up time (weeks) Number of studies Test of hetergeneity Analysis model Results RR (95% CI) P-value
   I2 P   LAM + ADV (n/N) ETV (n/N)   
12 4 0% 0.43 Fixed effect model 37/102 42/110 0.91[0.65,1.29] 0.61
24 4 37% 0.19 Fixed effect model 69/102 79/110 0.83[0.47,1.49] 0.54
48 4 68% 0.03 Randomed effect model 128/140 120/147 1.09[0.95,1.25] 0.21
96 3 43% 0.17 Fixed effect model 104/108 91/105 1.11[1.02,1.21] 0.01