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Table 3 Biochemical response results

From: Efficacy and resistance in de novo combination lamivudine and adefovir dipivoxil therapy versus entecavir monotherapy for the treatment-naive patients with chronic hepatitis B: a meta-analysis

Follow up time (weeks)

Number of studies

Test of hetergeneity

Analysis model

Results

RR (95% CI)

P-value

  

I2

P

 

LAM + ADV (n/N)

ETV (n/N)

  

12

4

0%

0.43

Fixed effect model

37/102

42/110

0.91[0.65,1.29]

0.61

24

4

37%

0.19

Fixed effect model

69/102

79/110

0.83[0.47,1.49]

0.54

48

4

68%

0.03

Randomed effect model

128/140

120/147

1.09[0.95,1.25]

0.21

96

3

43%

0.17

Fixed effect model

104/108

91/105

1.11[1.02,1.21]

0.01