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Table 5 Multivariate analysis of the factors affecting IFN α-2b therapeutic efficacy

From: Correlation between the suppressor of cytokine signaling-1 and 3 and hepatitis B virus: possible roles in the resistance to interferon treatment

Prognostic factors Regression coefficent Standard error Z value P value OR value 95% confidence interval
Age 1.03 0.77 1.33 0.18 2.80 [-0.48~2.54]
Gender 0.32 0.55 0.58 0.03 1.37 [0.75~1.39]
Genotype (A/B/C) 0.96 0.27 3.51 0.04 2.62 [0.73~1.50]
HBeAg (+/–) 0.86 0.31 2.80 0.75 2.37 [-0.26~1.47]
HBeAb (+/–) -0.80 0.27 -2.92 0.63 0.45 [-1.34~1.27]
ALT (IU/L) -0.58 0.32 -1.82 0.07 0.56 [-1.21~0.05]
AST (IU/L) -1.93 0.34 -5.65 0.96 0.14 [-2.60~1.26]
ALB (g/L) 0.17 0.77 0.22 0.83 1.62 [-1.35~1.68]
TBIL (mg/dL) 0.001 0.004 1.40 0.16 1.00 [1.00~1.24]
CHE (U/L) 2.18 1.23 1.78 0.08 8.91 [0.80-99.22]
CREA (mg/dL) -0.04 0.03 -1.55 0.12 0.96 [0.91~1.01]
INR for PT -0.003 0.001 -1.94 0.05 0.99 [0.99~1.00]
HBV-DNA 0.003 0.001 2.03 0.04 1.00 [1.00~1.01]
SOCS-1 -3.67 1.49 -2.47 0.03 0.03 [0.01~0.47]
SOCS-3 -2.50 1.24 -2.02 0.04 0.08 [0.01~0.93]
Cons -0.11 4.07 -0.03 0.98