Plaque reduction neutralization antibody test does not accurately predict protection against dengue infection in Ratchaburi cohort, Thailand

Table 2 Pre-existing PRNT50 titer and subsequent dengue infection in subjects with high titer (>90) to subsequent infecting serotype

Subject code	PRNT50 titer (Feb 2006)					Date of illness	Clinical diagnosis	ELISA test result^a	Serotype isolated
Subject code	D1	D2	D3	D4	JE	Date of illness	Clinical diagnosis	ELISA test result^a	Serotype isolated
06-043	121	224	83	<10	11	14/8/2006	DF	Secondary	D1
05-021	133	<10	<10	<10	72	26/4/2006	DF	Secondary	D1
05-074	173	1136	73	31	503	9/5/2006	DF	Secondary	D1
06-082	317	<10	18	<10	760	14/6/2006	Viral infection	Secondary	D1
01-286	581	<10	<10	<10	<10	19/4/2006	DF	Secondary	D1
01-141	1848	821	4521	328	738	6/11/2006	Pharyngitis	Secondary	D1
07-119	5291	84	332	98	207	28/7/2006	DF	Secondary	D4
05-244	4916	1305	1006	145	393	21/9/2006	DF	Secondary	D4
04-378	11682	853	417	261	5615	5/7/2006	DF	Secondary	D4

^aELISA result showed either primary or secondary infection.
D: dengue virus; DF: dengue fever; JE: Japanese encephalitis virus; PRNT50: 50% plaque reduction neutralization.

ISSN: 1743-422X