Skip to main content

Advertisement

Table 1 Histopathological changes of immune organs and lungs at different days post-inoculation (DPI)

From: Comparative analysis of apoptotic changes in peripheral immune organs and lungs following experimental infection of piglets with highly pathogenic and classical porcine reproductive and respiratory syndrome virus

Group DPI* Histological lesion score#(No. of piglets with lesions/no. of piglets examined)
   Tonsil ILN Spleen Lung
   a b a b a b c
1 0 0 0 0 0 0 0 0
  3 1 (1/3) 0 1 (2/3) 1 (1/3) 1 (2/3) 0 1 (1/3)
  7 2 (3/3) 1 (1/3) 1.5 (2/3) 1 (2/3) 1 (2/3) 1.5 (2/3) 1 (2/3)
  10 3 (3/3) 2.7 (3/3) 1.7 (3/3) 1.7 (3/3) 2 (3/3) 2 (2/3) 3 (3/3)
  14 3 (3/3) 3 (3/3) 3 (3/3) 2 (3/3) 3 (3/3) 2 (3/3) 4 (3/3)
2 0 0 0 0 0 0 0 0
  3 0 0 0 0 0 0 0
  7 2 (1/3) 0 1 (2/3) 0 0 1 (1/3) 1 (1/3)
  10 2 (2/3) 1.3 (3/3) 1 (2/3) 0 1 (2/3) 0 1.3 (3/3)
  14 1 (1/3) 1 (2/3) 1 (2/3) 1 (2/3) 1 (2/3) 1.5 (2/3) 1.3 (2/3)
  1. * Days post-inoculation when pigs were necropsied.
  2. # Mean histological lesion score of piglets with lesions.
  3. a Histological lymphoid depletion score: 0, normal; 1, mild; 2, moderate; 3, severe.
  4. b Inflammation and replacement of follicles score: 0, normal; 1, mild; 2, moderate; 3, severe.
  5. c Interstitial pneumonia score: 0, no microscopic lesions; 1, mild interstitial pneumonia; 2, moderate multifocal interstitial pneumonia; 3, moderate diffuse interstitial pneumonia; 4, severe interstitial pneumonia.