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Table 3 Sequences of reverted G367R env around CD4 binding site

From: Identification of an env-defective HIV-1 mutant capable of spontaneous reversion to a wild-type phenotype in certain T-cell lines

  HIV Env 365 366 367 368 369 370  
HXB2D A AGA GAA CAA TTT GGA AAT AAT AAA ACA ATA ATC TTT AAG CAA TCC TCA GGA GGG GAC CCA GAA ATT GTA CGC
G367R A AGA GAA CAA TTT GGA AAT AAT AAA ACA ATA ATC TTT AAG CAA TCC TCA GGA A GG GAC CCA GAA ATT GTA CGC
R1-MT2 A AGA GAA CAA TTT GGA AAT AAT AAA ACA ATA ATC TTT AAG CAA TCC TCA GGA GGG GAC CCA GAA ATT GTA CGC
R2-MT2 A AGA GAA CAA TTT GGA AAT AAT AAA ACA ATA ATC TTT AAG CAA TCC TCA GGA GGG GAC CCA GAA ATT GTA CGC
R3-MT2 A AGA GAA CAA TTT GGA AAT AAT AAA ACA ATA ATC TTT AAG CAA TCC TCA GGA GGG GAC CCA GAA ATT GTA CGC
R1-SupT1 A AGA GAA CAA TTT GGA AAT AAT AAA ACA ATA ATC TTT AAG CAA TCC TCA GGA GGG GAC CCA GAA ATT GTA CGC
R2-SupT1 A AGA GAA CAA TTT GGA AAT AAT AAA ACA ATA ATC TTT AAG CAA TCC TCA GGA GGG GAC CCA GAA ATT GTA CGC
  1. HXB2D represents wt, G367R represents the mutant plasmid, R1-3 represent the reverted viruses recovered, respectively, from G367R + VSV-G infected MT2 or SupT1 cells when seeded at cell numbers of 105, 104 or 102.
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Virology Journal

ISSN: 1743-422X