Sequencing and molecular characterization of CTNCEC25, a China fixed rabies virus vaccine strain CTN-1 adapted to primary chicken embryo cells

Table 4 Comparison of the sequence difference between the genomes of the CTNCEC25 and CTN-1 strains

Genome location^α	Protein position	Nucleotide/amino acid substitution (CTN-1 → CTNCEC25)
461	N	G → A/-^b
2476	P	G → -^c/-
2792	M	T → G/Leu → Arg
3068	M	C → T/Ser → Leu
3812	G-147	A → G/Lys → Glu
4371	G-333	G → A/Arg → Gln
4538	G	G → A/Glu → Lys
4635	G	C → A	/Pro → Gln
4636	G	A → G	/Pro → Gln
4826	G	T → C/Ser → Pro
5251	G	C → A/-
6289	L	A → G/-
7078	L	G → A/-
7750	L	G → A/-
9886	L	G → T/-
10141	L	A → G/-
10212	L	G → A/Arg → Lys

^αPosition from the 5′ terminal region of the full-genome sequence of the CTN-1 strain.
^bAmino acid synonymous mutation.
^cNucleotide deletion.

ISSN: 1743-422X