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Table 2 Conserved and variable regions of HCV in the nucleotide sequence of three genomic regions (5′ UTR, core, NS5B) among the two groups

From: Occurrence of genetic modifications in core, 5′UTR and NS5b of HCV associated with viral response to treatment

Treatment groups 5′UTR P values Core P values NS5B P values
Conserved region Variable Region Conserved region Variable region Conserved region Variable region
Group 1 (n = 75) 30-70, 70–84, 90–105, 124–140, 153-170 4-29 <0.001 70-91, 100–114, 120–142, 224-254 20-39, 143–169 320-341 <0.043 134-144, 353–370, 400-419 20-40, 60–87, 90–111, 420–439, 510–520, 600-619 <0.003
Group 2 (n = 75) 32-54, 61–80, 81–101, 120–135, 136–145, 150–164, 200-223 1-31, 104-119 <0.001 23-45, 67–91, 111–124, 222–252, 1-20, 254–267, 300–320, 354-378 <0.64 24- 38, 134- 151 1-20, 100–131, 200–237, 500-532, 610–624, 650-672 <0.001