Figure 2

HSP90 inhibitors reduced PRRSV production. (A) MARC-145 cells and (B) PAMs were infected and treated with different concentrations of drugs. The culture supernatants were collected at 24 h.p.i and viral titers were determined by calculating CCID₅₀. Data are mean ± SD, n = 3, and significant differences compared with DMSO (in MARC-145 cells) or no drug (in PAMs) treatment group, respectively, are denoted by ^*(P < 0.05).