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Table 1 Flow cytometry analysis of splenic CD4+ and CD8+ cells inside the proliferation gate for mice immunized with the experimental oral PCV2 vaccine

From: Chitosan microparticles loaded with yeast-derived PCV2 virus-like particles elicit antigen-specific cellular immune response in mice after oral administration

   Oral vaccine Non-immunized
CD4+ Non-stimulated 29.37 ± 2.04 13.08 ± 4.83
PCV2-stimulated 48.60 ± 6.92 28.30 ± 8.83
CD8+ Non-stimulated 38.16 ± 5.02 19.39 ± 5.27
PCV2-stimulated 63.26 ± 1.23 32.95 ± 1.14
  1. The table shows the percentage of CFSE-stained CD4+ and CD8+ cells (derived from orally immunized and non-immunized mice) present in the proliferation gate after re-stimulation (or vehicle stimulation) with PCV2 virions. Data represent the mean ± standard deviation of two independent experiments.
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Virology Journal

ISSN: 1743-422X