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Figure 5 | Virology Journal

Figure 5

From: Chitosan microparticles loaded with yeast-derived PCV2 virus-like particles elicit antigen-specific cellular immune response in mice after oral administration

Figure 5

Murine T-cell responses elicited by immunization with a commercial porcine circovirus type 2 (PCV2) vaccine. The horizontal and vertical axes denote the fluorescence intensity (CFSE) and the number of acquired events, respectively. The CD4+ (left) and CD8+ (right) T-cell populations in the spleens of mice immunized subcutaneously with a commercially available PCV2 vaccine, CircoFLEXTM. Splenocytes were harvested 8 weeks after primary immunization and re-stimulated in vitro with PK15-derived PCV2 virions. Cells exposed to PCV2 virions are shown in light red and those not exposed to PCV2 virions are shown in purple (vehicle). The results show representative histograms from two independent experiments.

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