|
Days collectedb
|
Virusa
|
Lung
|
Nose
|
|---|
|
Mean titer ± SDc
|
Mean titer ± SDc
|
|---|
| | |
(log10PFU g−1)
|
(log10PFU ml−1)
|
|---|
|
3
|
RSV-Long
|
4.52 ± 0.29
|
3.62 ± 0.52
|
|
rLong
|
3.20 ± 0.18
|
2.50 ± 0.12
|
|
rLong-∆G-EGFP
|
2.76 ± 0.36
|
<1.98
|
|
5
|
RSV-Long
|
4.42 ± 0.60
|
3.48 ± 0.25
|
|
rLong
|
2.86 ± 0.32
|
2.05 ± 0.08
|
|
rLong-∆G-EGFP
|
<2.68
|
<1.98
|
|
7
|
RSV-Long
|
2.95 ± 0.224
|
2.65 ± 0.15
|
|
rLong
|
<2.68
|
<1.98
|
| |
rLong-∆G-EGFP
|
<2.68
|
<1.98
|
- aBALB/c mice were inoculated with 105 PFU of (recombinant) virus. bLungs and nasal washes were collected, and virus titers were determined on the indicated day: 3, 5, or 7. cThe lower limits of detection for virus in the lungs and nose were 2.68 log10 PFU g−1 and 1.98 log10 PFU ml−1, respectively. Each group consisted of six animals.
