Skip to main content
Figure 3 | Virology Journal

Figure 3

From: The CD8 Antiviral Factor (CAF) can suppress HIV-1 transcription from the Long Terminal Repeat (LTR) promoter in the absence of elements upstream of the CATATAA box

Figure 3

Role of TAR in CAF suppression of HIV-1 LTR. Schematic of the TAR from HIV-1 LTR with the arrows indicating the sites at which it was cleaved, and the shadow, the intervening region that was deleted (Panel A). Reporter gene product (CAT) expression in cells pretreated with Hanks buffer (-CAF) or conditioned culture medium from a transformed CD8+ T cell line (+CAF) and transfected with the BstdelTAR construct, containing 3 SpI sites and TATA box (Panel B) Results are representative from at least 2 independent experiments conducted in triplicate. *, p < 0.05; ns, not significant.

Back to article page

Virology Journal

ISSN: 1743-422X