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Figure 9 | Virology Journal

Figure 9

From: Effective suppression of Dengue virus using a novel group-I intron that induces apoptotic cell death upon infection through conditional expression of the Bax C-terminal domain

Figure 9

DNA Fragmentation Assay : Clonal Aedes albopictus C6/ 36 cells transformed with αDENV -U143-FL, αDENV -ΔU143-ΔN Bax or αDENV-U143-ΔN Bax were each challenged with one of four known DENV serotypes (MOI 0.1). At 4 dpi (for DENV) cells were pelleted, lysed, and analyzed as described in Methods. Uninfected clonal and wild type C6/36 cells were also assayed as an additional negative control.

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