Figure 1
From: Comparison of multiple DNA vaccines for protection against cytomegalovirus infection in BALB/c mice
Bodyweight changes after virus challenge. Mice were immunized 1 to 4 times (A-D) at an interval of 2 weeks, with 100 μg plasmid DNAs encoding M04, M84, M105, IE-1and M55, respectively. Two weeks after the final immunization, mice were challenged with a lethal dose (3 × LD50) of MCMV and the body weights were measured within 3 weeks after the challenge. Data points represent mean ± SD of each group. a. Significant difference compared with control group (P < 0.05). b. Significant difference compared with M55 group (P < 0.05).