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Table 2 Closest neighbour to the 2003 and 2010 samples based on phylogenetic analysis

From: Genetic characterization of a Coxsackie A9 virus associated with aseptic meningitis in Alberta, Canada in 2010

Gene fragment

Closest neighbour to 2003

Closest neighbour to 2010

5’NCR

EV74

EV74

VP4

EV101

EV101

VP2

CVA-9

CVA-9

VP3

CVA-9

CVA-9

VP1

CVA-9

CVA-9

2A Protease

Echo 25

Echo 25

2B Protein

CVB-5 and echo14

CVB-5 and echo14

2C Helicase

Echo 25

CVB-6

3A protein

Echo 16 and CVB-6

EV 86

3B Protein (VPg)

Echo 14 and CVB-5

Echo 14 and CVB-5

3C Protease

Echo 13

EV 100

3D Protein (Pol)

Echo 13

EV 86

  1. Phylogenetic analysis was performed using all the available prototype sequences belonging to enterovirus species B.
  2. Phylogenetic tree is based on complete nucleotide sequence of the VP2 and VP4 genes; GenBank numbers for the prototype sequences used were D00627_CVA-9; M16560_CVB1; AF085363_CVB2; M16572_CVB3; X05690_CVB4; AF114383_CVB5; AF105342_CVB6; AF029859_E1; AY302545_E2; AY302553_E3; AY302557_E4; AF083069_E5; AY302558_E6; AY302559_E7; X84981_E9; X80059_E11; X79047_E12; AY302539_E13; AY302540_E14; AY302541_E15; AY302542_E16; AY302543_E17; AF317694_E18; AY302544_E19; AY302546_E20; AY302547_E21; AY302548_E24; AY302549_E25; AY302550_E26; AY302551_E27; AY302552_E29; AF162711_E30; AY302554_E31; AY302555_E32; AY302556_E33; AY302560_EV69; AF241359_EV73; AY556057_EV74; AY556070_EV75; AJ493062_EV77; AY843297_EV79; AY843298_EV80; AY843299_EV81; AY843300_EV82; AY843301_EV83; DQ902712_EV84; AY843303_EV85; AY843304_EV86; AY843305_EV87; AY843306_EV88; AY843307_EV97; NC_013115.1_EV107; DQ902713_EV100; AY843308_EV101. The GenBank numbers for the in-house sequenced samples from 2003 and 2010 are JQ837913 and JQ837914.