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Table 4 Uni- and multivariate analysis on risk factors associated with emergence of rtM204 change

From: Epidemiological, virological and clinical characteristics of HBV infection in 223 HIV co-infected patients: a French multi-centre collaborative study

  rtM204 change Univariate analysis Multivariate analysis
Variable % p OR 95% CI p
Gender   0.025    
men 29.2     
Women 12.2     
Country of origine   0.036    
Europe 36.4     
Maghreb 29.4     
Sub-Saharan Africa 15.7     
3TC or FTC treatment   <0.001    
Never 2.1   1   
Ever 31.7   13 1.7–99.2 0.013
  Presence vs. absence of rtM204 change     
Age 44.8 vs 40.9 <0.001 1.066 1.02–1.11 0.005
CD4 count 399 vs 307 0.002 1.001 1.000–1.003 0.038
T 1.30 vs 3.41 <0.001 0.503 0.37–0.69 <0.001
  1. Tested variables were: gender, age, geographic origin, mode of contamination, lamivudine treatment, HBV genotype, CD4 cell count, HIV viral load. Analysis was performed on 205 patients among whom 55 carried an rtM204 change.