Epidemiological, virological and clinical characteristics of HBV infection in 223 HIV co-infected patients: a French multi-centre collaborative study

Table 4 Uni- and multivariate analysis on risk factors associated with emergence of rtM204 change

	rtM204 change	Univariate analysis	Multivariate analysis
Variable	%	p	OR	95% CI	p
Gender		0.025
men	29.2
Women	12.2
Country of origine		0.036
Europe	36.4
Maghreb	29.4
Sub-Saharan Africa	15.7
3TC or FTC treatment		<0.001
Never	2.1		1
Ever	31.7		13	1.7–99.2	0.013
	Presence vs. absence of rtM204 change
Age	44.8 vs 40.9	<0.001	1.066	1.02–1.11	0.005
CD4 count	399 vs 307	0.002	1.001	1.000–1.003	0.038
T	1.30 vs 3.41	<0.001	0.503	0.37–0.69	<0.001

Tested variables were: gender, age, geographic origin, mode of contamination, lamivudine treatment, HBV genotype, CD4 cell count, HIV viral load. Analysis was performed on 205 patients among whom 55 carried an rtM204 change.

ISSN: 1743-422X