Figure 7
Performance of RAL linear regression model on population unseen data. Scatterplot of measured FC vs. predicted FC for the first and second order linear model on unseen data. Horizontal and vertical axes are drawn through the biological cutoff value of FC = 2.0. (A) The R2 performance was 0.76 (first order), 0.78 (second order) and 0.75 (geno2pheno). (B) Samples called resistant by ANRS, Rega and Stanford are predicted resistant by the linear model. (C) Samples called susceptible by ANRS, Rega and Stanford are predicted susceptible by the linear model. (D) Samples with discordant call between the genotypic algorithms.