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Figure 4 | Virology Journal

Figure 4

From: Lineage shift in Indian strains of Dengue virus serotype-3 (Genotype III), evidenced by detection of lineage IV strains in clinical cases from Kerala

Figure 4

a. The Capsid-PrM-Envelope sequence region used in phylogeneticAnalysis. The positions are numbered with reference to the NCBI strain NC_001475. b. Phylogenetic analysis using Maximum-Likelihood method. Nucleotide sequences of a 1740 bp partial C-PrM-E coding region from 158 dengue serotype-3 virus representing the Indian, Asian and South American strains were used in the analysis. Analysis was carried out with 1000 bootstrap replications employing a Tamurai-Nei substitution model with Gamma distributed (G) rate among sites. The scale bar represents the number of nucleotide substitutions per site. Boot–strap values more than 70% are shown. GenBank accession number, place and year of isolation are indicated. Sequences obtained in the study are shown with a filled triangle (‘▲’). To improve clarity, the clades representing the related strains from Singapore, Puerto-Rico, Sri Lanka, Indonesia and Taiwan are shown compressed.

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