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Table 2 Differentially expressed genes in the comparison of VIR versus BDL

From: Transcriptome analysis of primary monocytes from HIV-positive patients with differential responses to antiretroviral therapy

ProbeID

Gene symbol

Entrez gene name

logFC

FDR

4540239

DEFA1

Defensin, alpha 1

-2.06

0.018

2970747

DEFA3

Defensin, alpha 3

-1.74

0.012

7150170

LOC728358

NA

-1.54

0.020

50088

HCFC1R1

Host cell factor C1 regulator 1 (XPO1 dependent)

-1.47

0.003

2750647

C20orf27

Chromosome 20 open reading frame 27

-1.17

0.005

3390068

E4F1

E4F transcription factor 1

-1.09

0.003

4280661

TMUB2

Transmembrane and ubiquitin-like domain containing 2

-1.08

0.003

2490333

ZNF467

Zinc finger protein 467

-1.06

0.036

1820053

SLC43A2

Solute carrier family 43, member 2

-1.05

0.010

6940647

C16orf58

Chromosome 16 open reading frame 58

-1.01

0.034

1570255

DEF6

Differentially expressed in FDCP 6 homolog (mouse)

-1.00

0.017

2630017

TPST2

Tyrosylprotein sulfotransferase 2

1.00

0.027

5810008

DLGAP4

Discs, large (Drosophila) homolog-associated protein 4

1.01

0.017

4050475

KIAA0319L

KIAA0319-like

1.01

0.048

730632

LSP1

Lymphocyte-specific protein 1

1.02

0.017

7160711

MAP2K3

Mitogen-activated protein kinase kinase 3

1.02

0.020

4200025

OAF

OAF homolog (Drosophila)

1.02

0.008

1510414

MGRN1

Mahogunin ring finger 1, E3 ubiquitin protein ligase

1.04

0.017

2490072

PRAM1

PML-RARA regulated adaptor molecule 1

1.04

0.020

7320494

ZFPM1

Zinc finger protein, FOG family member 1

1.04

0.003

6450092

C5AR1

Complement component 5a receptor 1

1.05

0.031

7570068

EP300

E1A binding protein p300

1.05

0.044

770168

CLPTM1

Cleft lip and palate associated transmembrane protein 1

1.06

0.005

1070044

GMIP

GEM interacting protein

1.06

0.017

7400053

SLC22A18

Solute carrier family 22, member 18

1.06

0.041

3800307

SHKBP1

SH3KBP1 binding protein 1

1.07

0.005

830750

NCF1B

Neutrophil cytosolic factor 1B pseudogene

1.07

0.012

7050484

ZYX

Zyxin

1.08

0.008

4640064

LTBR

Lymphotoxin beta receptor (TNFR superfamily, member 3)

1.08

0.008

2000224

FAM89B

Family with sequence similarity 89, member B

1.09

0.018

1940021

GRN

Granulin

1.09

0.017

2480288

GPAA1

Glycosylphosphatidylinositol anchor attachment 1

1.09

0.022

2970356

ALDH3B1

Aldehyde dehydrogenase 3 family, member B1

1.13

0.005

5570767

PPP2R1A

Protein phosphatase 2, regulatory subunit A, alpha

1.13

0.006

5890072

TRAPPC9

Trafficking protein particle complex 9

1.14

0.001

6960026

STXBP2

Syntaxin binding protein 2

1.14

0.000

5910019

C1QB

Complement component 1, q subcomponent, B chain

1.17

0.019

270437

ACTN4

Actinin, alpha 4

1.18

0.000

5570242

PFKL

Phosphofructokinase, liver

1.20

0.004

840669

LOC654346

NA

1.22

0.017

4920546

ARSA

Arylsulfatase A

1.24

0.001

2650092

JOSD2

Josephin domain containing 2

1.25

0.000

4760255

ARHGDIA

Rho GDP dissociation inhibitor (GDI) alpha

1.26

0.004

6480333

TCIRG1

T-cell, immune regulator 1, ATPase, H + transporting, lysosomal V0 subunit A3

1.29

0.001

4180494

ITGAL

Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

1.30

0.010

6620609

ABTB1

Ankyrin repeat and BTB (POZ) domain containing 1

1.30

0.021

150154

FAM108A3

Family with sequence similarity 108, member A3, pseudogene

1.30

0.000

4730349

PNKD

Paroxysmal nonkinesigenic dyskinesia

1.31

0.040

2140392

ZNF580

Zinc finger protein 580

1.32

0.006

4890068

MAP3K11

Mitogen-activated protein kinase kinase kinase 11

1.32

0.001

7550500

JUNB

Jun B proto-oncogene

1.39

0.028

7650128

ECGF1

Thymidine phosphorylase

1.40

0.012

4220603

SPI1

Spleen focus forming virus (SFFV) proviral integration oncogene spi1

1.43

0.005

5090632

LGALS9

Lectin, galactoside-binding, soluble, 9

1.45

0.006

20673

BSG

Basigin (Ok blood group)

1.61

0.000

770754

TTYH3

Tweety homolog 3 (Drosophila)

1.72

0.001

6580059

UCP2

Uncoupling protein 2 (mitochondrial, proton carrier)

1.79

0.023

130403

RNF19B

Ring finger protein 19B

1.83

0.004

6370315

HLA-DRB5

Major histocompatibility complex, class II, DR beta 5

5.66

0.012

  1. The differentially expressed genes were sorted by fold change.
  2. Gene symbols in italic indicated genes in HIV interaction database.
  3. FDR: false discovery rate; NA: not available.