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Table 2 Differentially expressed genes in the comparison of VIR versus BDL

From: Transcriptome analysis of primary monocytes from HIV-positive patients with differential responses to antiretroviral therapy

ProbeID Gene symbol Entrez gene name logFC FDR
4540239 DEFA1 Defensin, alpha 1 -2.06 0.018
2970747 DEFA3 Defensin, alpha 3 -1.74 0.012
7150170 LOC728358 NA -1.54 0.020
50088 HCFC1R1 Host cell factor C1 regulator 1 (XPO1 dependent) -1.47 0.003
2750647 C20orf27 Chromosome 20 open reading frame 27 -1.17 0.005
3390068 E4F1 E4F transcription factor 1 -1.09 0.003
4280661 TMUB2 Transmembrane and ubiquitin-like domain containing 2 -1.08 0.003
2490333 ZNF467 Zinc finger protein 467 -1.06 0.036
1820053 SLC43A2 Solute carrier family 43, member 2 -1.05 0.010
6940647 C16orf58 Chromosome 16 open reading frame 58 -1.01 0.034
1570255 DEF6 Differentially expressed in FDCP 6 homolog (mouse) -1.00 0.017
2630017 TPST2 Tyrosylprotein sulfotransferase 2 1.00 0.027
5810008 DLGAP4 Discs, large (Drosophila) homolog-associated protein 4 1.01 0.017
4050475 KIAA0319L KIAA0319-like 1.01 0.048
730632 LSP1 Lymphocyte-specific protein 1 1.02 0.017
7160711 MAP2K3 Mitogen-activated protein kinase kinase 3 1.02 0.020
4200025 OAF OAF homolog (Drosophila) 1.02 0.008
1510414 MGRN1 Mahogunin ring finger 1, E3 ubiquitin protein ligase 1.04 0.017
2490072 PRAM1 PML-RARA regulated adaptor molecule 1 1.04 0.020
7320494 ZFPM1 Zinc finger protein, FOG family member 1 1.04 0.003
6450092 C5AR1 Complement component 5a receptor 1 1.05 0.031
7570068 EP300 E1A binding protein p300 1.05 0.044
770168 CLPTM1 Cleft lip and palate associated transmembrane protein 1 1.06 0.005
1070044 GMIP GEM interacting protein 1.06 0.017
7400053 SLC22A18 Solute carrier family 22, member 18 1.06 0.041
3800307 SHKBP1 SH3KBP1 binding protein 1 1.07 0.005
830750 NCF1B Neutrophil cytosolic factor 1B pseudogene 1.07 0.012
7050484 ZYX Zyxin 1.08 0.008
4640064 LTBR Lymphotoxin beta receptor (TNFR superfamily, member 3) 1.08 0.008
2000224 FAM89B Family with sequence similarity 89, member B 1.09 0.018
1940021 GRN Granulin 1.09 0.017
2480288 GPAA1 Glycosylphosphatidylinositol anchor attachment 1 1.09 0.022
2970356 ALDH3B1 Aldehyde dehydrogenase 3 family, member B1 1.13 0.005
5570767 PPP2R1A Protein phosphatase 2, regulatory subunit A, alpha 1.13 0.006
5890072 TRAPPC9 Trafficking protein particle complex 9 1.14 0.001
6960026 STXBP2 Syntaxin binding protein 2 1.14 0.000
5910019 C1QB Complement component 1, q subcomponent, B chain 1.17 0.019
270437 ACTN4 Actinin, alpha 4 1.18 0.000
5570242 PFKL Phosphofructokinase, liver 1.20 0.004
840669 LOC654346 NA 1.22 0.017
4920546 ARSA Arylsulfatase A 1.24 0.001
2650092 JOSD2 Josephin domain containing 2 1.25 0.000
4760255 ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.26 0.004
6480333 TCIRG1 T-cell, immune regulator 1, ATPase, H + transporting, lysosomal V0 subunit A3 1.29 0.001
4180494 ITGAL Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.30 0.010
6620609 ABTB1 Ankyrin repeat and BTB (POZ) domain containing 1 1.30 0.021
150154 FAM108A3 Family with sequence similarity 108, member A3, pseudogene 1.30 0.000
4730349 PNKD Paroxysmal nonkinesigenic dyskinesia 1.31 0.040
2140392 ZNF580 Zinc finger protein 580 1.32 0.006
4890068 MAP3K11 Mitogen-activated protein kinase kinase kinase 11 1.32 0.001
7550500 JUNB Jun B proto-oncogene 1.39 0.028
7650128 ECGF1 Thymidine phosphorylase 1.40 0.012
4220603 SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1 1.43 0.005
5090632 LGALS9 Lectin, galactoside-binding, soluble, 9 1.45 0.006
20673 BSG Basigin (Ok blood group) 1.61 0.000
770754 TTYH3 Tweety homolog 3 (Drosophila) 1.72 0.001
6580059 UCP2 Uncoupling protein 2 (mitochondrial, proton carrier) 1.79 0.023
130403 RNF19B Ring finger protein 19B 1.83 0.004
6370315 HLA-DRB5 Major histocompatibility complex, class II, DR beta 5 5.66 0.012
  1. The differentially expressed genes were sorted by fold change.
  2. Gene symbols in italic indicated genes in HIV interaction database.
  3. FDR: false discovery rate; NA: not available.