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Figure 5 | Virology Journal

Figure 5

From: Whole genome sequencing and de novo assembly identifies Sydney-like variant noroviruses and recombinants during the winter 2012/2013 outbreak in England

Figure 5

Norovirus phylogenies for ORF1 and ORF2/3. Maximum likelihood trees for ORF1 and ORF2/ORF3 regions based on an alignment of 23 norovirus sequences from England and Jersey isolated during winter 2012/13 and two GII.4 reference genomes: New Orleans 2009 and Sydney 2012 (represented with yellow and blue filled circles, respectively). Trees were constructed in PhyML (27) under an HKY85 model of nucleotide substitution, midpoint rooted and bootstrapped with 100 replicates. The bootstrap support is provided for each node (in bold). Clades are coloured according to the reference strain with which they appear to cluster. The dashed line highlights phylogenetic incongruity between ORF1 and ORF2/ORF3, proposed to have arisen by recombination.

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