Skip to main content

Table 3 Results of determination on HBV DNA in serum and tissue samples

From: Histopathological changes in the liver of tree shrew (Tupaia belangeri chinensis) persistently infected with hepatitis B virus

Group Experimental no. HBV DNA in serum (Copies/ml)a HBV DNA in liver
Copies/μg liver DNAb Copiesc P-value
A (n = 6) A1 2.63 × 106 1.83 × 108 1.12 ± 0.99 × 108  
A2 5.22 × 103 1.27 × 108   
A3 8.74 × 106 5.17 × 108   
A4 1.09 × 106 2.64 × 108   
A5* - 7.61 × 104   
A6 2.42 × 105 4.36 × 107   
B (n = 3) B1 - 9.58 × 105 3.56 ± 5.22 × 105 0.039d
     0.400b
B2 - 3.91 × 104   0.400e
B3 - 7.04 × 104   
C (n = 4) C1 - 6.35 × 104 5.06 ± 2.18 × 104 0.011d
C2 - 1.90 × 104   
C3 - 6.63 × 104   
C4 - 5.34 × 104   
  1. aHBV DNA copy number ≥103 in serum is defined as a positive; bHBV DNA copy number ≥105 in liver tissue is defined as a positive; cResults are shown as mean ± SD; dCompared with group A; eCompared with group C.
  2. *: This animal had showed 1.1 × 107 copies/ml in serum, 3.73 × 105 and 1.82 × 108 copies/μg in liver at the time points of 60- and 72-Weeks after inoculation.