Figure 5From: Single dose of Glycoprotein K (gK)-deleted HSV-1 live-attenuated virus protects mice against lethal vaginal challenge with HSV-1 and HSV-2 and induces lasting T cell memory immune responsesCD4 and CD8 T lymphocyte counts and their activation in mock, vaccinated and vaccinated-challenged mice. No substantial changes in CD4 and CD8 population were noticed within mock, vaccinated and vaccinated-challenged group of mice. However, there was an increased CD8 + CD69+ T cell activation monitored in vaccinated-challenged mice compared to other groups (P < 0.05).Back to article page