Genetic variation in the 3’ untranslated region of dengue virus serotype 3 strains isolated from mosquitoes and humans in Brazil

Table 2 Amino acid differences among selected Brazilian DENV-3 and strains representative of the DENV-3 genotypes, compared to the prototype H87

Genotypes	GI			GII			GI	GII	GIV
Gene	Strain	PHIL/H87/1956 human	BR/74886/ 2002 human	BR/73354/2001 mosquitoes	BR/SP/V3456/2006 human	BR/SP/V3615/2007 human	INDO/PG86/2004 human	TAIWAN/TWmosq/ 1998 mosquitoes	TAHITI/136116/1994 human
Gene	Position	PHIL/H87/1956 human	BR/74886/ 2002 human	BR/73354/2001 mosquitoes	BR/SP/V3456/2006 human	BR/SP/V3615/2007 human	INDO/PG86/2004 human	TAIWAN/TWmosq/ 1998 mosquitoes	TAHITI/136116/1994 human
Capsid	C ₁₀₈	M	I	I	I	I
Capsid	C₁₁₂	T	A	A	A	A
prMembrane	prM₈₆	H	R	R	R	R
Envelope	E₈₁	I	V	V	V	V
	E₁₂₄	S	P	P	L	L	L	P
	E₁₃₂	H	Y	Y	Y	Y		Y
	E₁₆₉	A	T	T	T	T	V	V	V
	E₂₇₀	T	N	N	N	N		N
	E₃₀₁	L	T	T	T	T	S
	E₃₈₀	I			T	T
	E₃₈₃	K		N	N	N
	E₄₅₂	I	V	V	V	V
NS1	NS1₈₄	I			V
	NS1₉₄	T	I		I	I	I	I	I
	NS1₁₃₉	S	N		N	N	N	N	N
	NS1₃₃₉	N	S	S	S	S
NS2A	NS2A₃₇	L	F	F	F	F
	NS2A₁₅₈	I	M	M	M	M
	NS2A₁₇₅	I	V	V	V	V		V
	NS2A₁₉₅	T	A	A	A	A
NS2B	NS2B₆₀	V	I	I	I	I
NS2B	NS2B₁₀₉	I	V	V	V	V
NS3	NS3₁₁₅	I	T	T	T	T
NS3	NS3₄₅₂	V	A	A	A	A		A
NS4A	NS4A₉₉	D	E	E	E	A
NS4B	NS4B₂₁	V	I	I	I	I
NS4B	NS4B₁₃₈	V	I	I	I	I
NS5	NS5₉₇	V		L
	NS5₉₈	T		S
	NS5₁₀₁	R		*STOP
	NS5₁₀₅	K		T
	NS5₁₁₂	E		A
	NS5₁₁₄	V		R
	NS5₁₁₇	S		P
	NS5₁₂₇	M		R
	NS5₁₃₁	D		E
	NS5₁₃₃	F		D
	NS5₁₃₅	L		P
	NS5₂₂₉	S	A	A	A	A
	NS5₂₃₃	M		R
	NS5₂₈₈	S	N	N	N	N
	NS5₃₆₅	P	S	S	S	S
	NS5₃₇₁	K	R	R	R	R
	NS5₃₇₄	E	G	G	G	G
	NS5₃₈₉	R		K	K	K		K
	NS5₄₂₂	R	K	K	K	K
	NS5₄₂₉	E	D	D	D	D
	NS5₅₈₅	K	T	T	T	T
	NS5₆₃₉	L	P	P	P	P
	NS5₇₆₃	T	S	S	S	S	A	S	A
	NS5₈₃₅	D N	N	N	N

Blank cells indicate amino acid similarities to the prototype strain H87 (GenBank accession number M93130). *STOP: stop codon.

ISSN: 1743-422X