† For each category the median values (range) are indicated. In particular JCPyV loads values are expressed as log10 genome equivalent (gEq)/mL in urine and in plasma, and as log10 gEq/106 cells in PBMCs.
§: Disease Activity is indicated by scale, score or index specific for each disease assessed: for Cohort1 MS, Kurtzke Expanded Disability Status Scale (EDSS) is used. This scale ranges from 0 (normal neurological examination) to 10 (confined to bed); for PsA and RA (Cohort2), Disease Activity Score with a 28-joint count related to C-reactive protein (DAS28-CRP) is used, with a high score indicating more active disease; for AS (Cohort2), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) is used. This index ranges from 0 (no activity) to 10 (maximum activity); for Cohort3 CD, Pediatric Crohn's Disease Activity Index (PCDAI) is used (score ≤10: inactive disease; 10–30: mild disease; >30: moderate to severe disease).
* At t0, 1 patient (out of the 21 multiple sclerosis patients enrolled) do not perform the urine and blood sampling.