Figure 4

Alignment of partial nucleotide sequences of the rex gene for all patas and tantalus STLV-1 strains used in this study compared to other different HTLV-1 strains. The base deletions at position 5164 (ATK EMBL#) fro the tantalus strains, respectively, are shown as dashes which would create a frameshift and allow for missense translation of p27 Rex accordingly. p21 Rex would not be affected because it utilizes a translational start site downstream from the deletions. ATK is the consensus Japanese HTLV-1 strain used for comparative analysis with its translated amino acids displayed above each codon. Areas of identity are indicated by the symbol (•) and deletions shown by the symbol (―). Letters displayed in parenthesis below a sequence represent an alteration in an amino acid codon at that position. For clarity, the missense translations of the STLVs are not shown. The alignment was ended at the 5’ splice junction for rex located in the env gene of the viral genome.