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Table 3 Histological summary of infected six-week-old BALB/c mice euthanized at various time-points post-inoculation

From: Duck Tembusu virus exhibits neurovirulence in BALB/c mice

Tissues

Days post-infection

3

6

9

12

Brain

Control

-

-

-

-

Infected

1/3+

3/3++

3/3#

3/3++

Heart

Control

-

-

-

-

Infected

-

-

-

-

Lung

Control

-

-

-

-

Infected

-

-

-

-

Liver

Control

-

-

-

-

Infected

-

-

1/3++, 2/3#

-

Spleen

Control

-

-

-

-

Infected

1/3+

3/3+

3/3++

1/3+

Kidney

Control

-

-

-

-

Infected

-

-

2/3++, 1/3#

-

  1. -, none; +, 1–3 focal inflammatory infiltrates, perivascular cuffing and microglial hyperplasia per high power field (HPF); ++, lesions covering 25% of a HPF; #, lesions covering >75% of a HPF.
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Virology Journal

ISSN: 1743-422X