Table 1 HCV proteins involved in oxidative stress
HCV proteins | What they can do? |
|---|---|
Core protein, NS3, NS5A, E1, E2, NS4B | • Increase oxidative stress |
Core protein, NS5A, NS3 | • Increase calcium uptake by mitochondria |
|  | • Oxidation of mitochondrial glutathione leading to elevated ROS |