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Table 1 Amino acid homology between influenza A and B viral proteins

From: Cross-reactive human B cell and T cell epitopes between influenza A and B viruses

Protein name

Size in influenza Aa

Size in influenza Bb

Amino acid (aa) identityc

Polymerase basic 2 (PB2)

759 aa

770 aa

37%

Polymerase basic 1 (PB1)

757 aa

752 aa

58%

Polymerase acid (PA)

716 aa

726 aa

35%

Hemagglutinin (HA)

566 aa

584 aa, 585 aad

18%

Nucleoprotein (NP)

498 aa

560 aa

36%

Neuraminidase (NA)

469 aa

466 aa

20%

Matrix protein 1 (M1)

252 aa

248 aa

27%

Matrix protein 2 (M2)e

97 aa

109 aa

7%

Nonstructural protein 1 (NS1)

219 aa, 230 aaf

281 aa, 282 aag

14%

NS2/nuclear export protein (NEP)

121 aa

122 aa, 123 aah

21%

  1. aAmino acid sequences are from influenza A/California/07/2009(H1N1) (GenBank protein accession number: AFM72841, AFM72840, AFM72839, AFM72832, AFM72836, AFM72835, AFM72833, AFM72834, AFM72837 and AFM72838), A/Brisbane/10/2007(H3N2) (ACI26328, ACI26326, ACI26325, ACI26318, ACI26322, ACI26321, ACI26319, ACI26320, ACI26323 and ACI26324).
  2. bAmino acid sequences are from influenza B/Wisconsin/01/2010 (B/Yamagata/16/88-lineage) (AFH57963, AFH57962, AFH57961, AFH57953, AFH57958, AFH57957, AFH57954, AFH57955, AFH57959 and AFH57960) and B/Brisbane/60/2008 (B/Victoria/2/87-like lineage) (AFH57919, AFH57918, AFH57917, AFH57909, AFH57914, AFH57913, AFH57910, AFH57911, AFH57915 and AFH57916).
  3. cConserved amino acids among four viruses. Denominators are the proteins of A/California/07/2009(H1N1).
  4. d584 aa for B/Wisconsin/01/2010 and 585 aa for B/Brisbane/60/2008.
  5. eCorresponding influenza B virus protein is BM2 [19].
  6. f219 aa for A/California/07/2009(H1N1) and 230 aa for A/Brisbane/10/2007(H3N2).
  7. g281 aa for B/Wisconsin/01/2010 and 282 aa for B/Brisbane/60/2008.
  8. h122 aa for B/Wisconsin/01/2010 and 123 aa for B/Brisbane/60/2008.
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Virology Journal

ISSN: 1743-422X