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Table 1 Demographics of chronic HBV patients

From: Hepatitis B virus (HBV)-specific T-cell responses to recombinant HBV core protein in patients with normal liver function and co-infected with chronic HBV and human immunodeficiency virus 1 (HIV-1)

Parameter

Single HBV infection

HIV/HBV coinfection

 

HBeAg+

HBeAg-

P value

HBeAg+

HBeAg-

P value

No. of Subjects

8

8

 

11

14

 

Gender(no. male/female)

7/1

6/2

NSa

11/0

13/1

NSa

Age [median (range)] (yr)

36 (22-60)

38 (25-67)

NSb

34 (23-40)

32 (25-56)

NSb

ALT [median (range)] (U/L)

19.2 (6.1-53)c

23.7 (12.2-40)

NSb

22.4 (13.5-58)c

19.2 (13.7-38)

NSb

HBV DNAd [median (range)]

7.71 (0-9.04)

1.04 (0-4.32)

<0.01

6.85 (0-8.51)

1.35 (0-8.98)

<0.01

HIV RNAd [median (range)]

NA

NA

 

4.8 (0-5.4)

4.98 (0-5.9)

NSb

CD4 count [median (range)] (cells/ul)

NA

NA

 

452 (211-862)

332 (122-704)

NSb

  1. NS not significant, NA not applicable, aFisher’s exact test; bMann-Whitney U test; conly one patient had an ALT >40 U/L; dlog10, +postive; -negtive.