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Table 1 Demographics of chronic HBV patients

From: Hepatitis B virus (HBV)-specific T-cell responses to recombinant HBV core protein in patients with normal liver function and co-infected with chronic HBV and human immunodeficiency virus 1 (HIV-1)

Parameter Single HBV infection HIV/HBV coinfection
  HBeAg+ HBeAg- P value HBeAg+ HBeAg- P value
No. of Subjects 8 8   11 14  
Gender(no. male/female) 7/1 6/2 NSa 11/0 13/1 NSa
Age [median (range)] (yr) 36 (22-60) 38 (25-67) NSb 34 (23-40) 32 (25-56) NSb
ALT [median (range)] (U/L) 19.2 (6.1-53)c 23.7 (12.2-40) NSb 22.4 (13.5-58)c 19.2 (13.7-38) NSb
HBV DNAd [median (range)] 7.71 (0-9.04) 1.04 (0-4.32) <0.01 6.85 (0-8.51) 1.35 (0-8.98) <0.01
HIV RNAd [median (range)] NA NA   4.8 (0-5.4) 4.98 (0-5.9) NSb
CD4 count [median (range)] (cells/ul) NA NA   452 (211-862) 332 (122-704) NSb
  1. NS not significant, NA not applicable, aFisher’s exact test; bMann-Whitney U test; conly one patient had an ALT >40 U/L; dlog10, +postive; -negtive.