Figure 2

Whole body weight change and spleen weight in AG129 mice during the course of TCRV infection. A) Body weight data are represented as the group mean and standard deviation of the percent change in weight of surviving animals relative to their starting weights, measured at 2-day intervals. B) Spleen weight data represent the mean and standard deviation from groups of 4 TCRV-infected mice sacrificed at the indicated times. Data from 1 sham-infected control animal per day are included for comparison. n=40, 36, 28, 20, 12, and 4 for the TCRV-infected mice, and n=10, 9, 7, 5, 3, and 1 mouse for the normal controls, on day 0, 2, 4, 6, 8, and 10, respectively. *P< 0.05, **P< 0.01, ****P< 0.001 compared to sham-infected animals.