Table 2 Clinical presentations of patients acquiring CVA6 and non-CVA6 enterovirus infection
From: Atypical hand-foot-mouth disease in children: a hospital-based prospective cohort study
CVA6 positive (N=81) | Non-CVA6* (N=20) | P value | |
|---|---|---|---|
Demographics | |||
Age (year) | 3.5 (±3.2) | 2.8 (±1.5) | 0.92 |
Male | 54 (67%) | 11 (55%) | 0.33 |
Female | 27 (33%) | 9 (45%) | |
Sites | |||
Limbs | 80 (99%) | 18 (90%) | 0.10 |
Arm/Leg/Thigh | 56 (69%) | 16 (80%) | 0.79 |
Trunk | 22 (27%) | 7 (35%) | 0.58 |
Buttocks | 25 (30%) | 6 (30%) | 1.00 |
Face | 34 (41%) | 8 (40%) | 0.80 |
Ear lobes | 11 (13%) | 0 | 0.12 |
Perioral area | 23 (28%) | 4 (20%) | 0.27 |
Morphology | |||
Large vesicles | 45 (56%) | 5 (25%) | 0.02 |
Symptoms | |||
Fever | 66 (80%) | 15 (75%) | 0.37 |
Sore throat | 49 (60%) | 10 (50%) | 0.45 |
Cough/rhinorrhea | 23 (28%) | 7 (35%) | 0.58 |
Vomit/diarrhea | 11 (13%) | 6 (30%) | 0.10 |
Skin lesions | |||
Itchiness | 27 (33%) | 5 (25%) | 0.60 |
Pigmentation | 6 (7%) | 3 (15%) | 0.34 |
Prickle | 2 (2%) | 0 (0%) | 1.00 |
Myoclonic jerks | 11 (13%) | 3 (15%) | 1.00 |
Hospitalization | |||
Days (days) | 3.4 (± 1.3) | 2.3 (± 0.6) | 0.24 |
Age (years) | 2.3 (± 3.1) | 2.3 (± 0.6) | 0.30 |