Figure 2

Mice immunized with rAd-M2 and rAd-NP are protected against weight loss when virus is inhaled, but not when virus is instilled. The average percent of starting weight for each group is shown for mice that were challenged by (A) instillation and (B) inhalation. Mice in each group (n = 5) were weighed individually on each day after challenge. Each graph shows the percent group mean change in weight relative to the baseline body weights, with error bars indicating the standard deviation for the group.