Figure 1
From: Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in cervical cancer
Hierarchical cluster tree of representation miRNAs in cell lines before and after treatment with the demethylating agent 5-AZA. Each row represented a miRNA and each column represented a sample. The miRNA clustering tree was shown on the left, and the sample clustering tree appeared at the top. The color scale shown at the top illustrated the relative expression level of a miRNA: red color represented a high expression level; green color represented a low expression level. The clustering was performed on differentially expressed miRNAs (differentially expressed in all 4 comparisons); the low intensity expressed miRNAs were filtered (which ForeGround- BackGround intensities were all <50 in all the samples). (A1: C33A treated with 5-AZA;A2: C33A; C1: Caski treated with 5-AZA; C2: Caski; H1: Hela treated with 5-AZA; H2: Hela; S1: Siha treated with 5-AZA; S2:Siha).