Figure 4

Infected B6.IDO−/− Mice Do Not Display An Altered LP-BM5 Viral Load. B6 and B6.IDO−/− mice were infected in parallel, with 5x10⁴ pfu, and splenic mRNA was extracted at 8 wpi. LP-BM5 Eco Gag and Def Gag mRNA were assessed by qRT-PCR, relative to β-actin [63]. Histograms represent the means, (n = 4), with indicated standard deviations. The patterns of the presented results are representative of three additional experiments, which provided a similar pattern of results. **p < 0.01; ***p < 0.001; ****p < 0.0001, in comparison to uninfected controls, as determined using one-way ANOVA.