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Table 1 Neutralization of HPeV1 to 6 by polyclonal Abs, read out of CPE at day 7 post infection

From: Growth characteristics of human parechovirus 1 to 6 on different cell lines and cross- neutralization of human parechovirus antibodies: a comparison of the cytopathic effect and real time PCR

 

CPE score day 7

 

aHPeV1-Ab2

aHPeV2-Ab2

aHPeV3 Ab2

aHPeV4 Ab2

aHPeV5 Ab2

No Ab

HPeV1- Harris 1

- *

4+

4+

4+

-

4+

HPeV2- 751312 1

4+

-

4+

4+

4+

4+

HPeV3- 150237 1

4+

4+

4+

4+

4+

4+

HPeV4- 251176 1

2+

4+

4+

-

1+

4+

HPeV5- 552322 1

2+

4+

4+

-

-

4+

HPeV6- 550389 1

3+

4+

4+

4+

2+

4+

  1. 1 100TCID50 infection on HT29 (HPeV1, 2, 4, 5) and Vero (HPeV3) cells.
  2. 2 Ab dilution 1:100.
  3. * - no CPE.
  4. 1+ 0- 25% CPE.
  5. 2+ 25-50% CPE.
  6. 3+ 50-75% CPE.
  7. 4+ 75-100% CPE.