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Figure 3 | Virology Journal

Figure 3

From: Prokaryote-expressed M2e protein improves H9N2 influenza vaccine efficacy and protection against lethal influenza a virus in mice

Figure 3

Protection against homologous lethal challenge by addition of M2e protein to vaccine. Groups of immunized mice and control mice were intranasally challenged with a lethal dose (2LD50) of A/chicken/Korea/ma163/04 (ma163/H9N2) influenza virus three weeks after boost vaccination. (A) Body weight changes and (B) survival were recorded for 14 days post-challenge. 1×M2e or 4×M2e mixed with inactivated H9N2 vaccine induced cross-protection against heterosubtypic avian H5N2 and human H3N2 influenza virus.

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Virology Journal

ISSN: 1743-422X