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  1. Case Report

    Encephalitis associated with human herpesvirus-7 infection in an immunocompetent adult

    Primary Human herpesvirus-7 (HHV-7) infection usually occurs during childhood and causes several clinical manifestations: mainly exanthem subitum (roseola infantum), followed by a lifelong latent state with possi...

    Mónica Parra, Adoración Alcala, Cristina Amoros, Anna Baeza, Antonio Galiana, David Tarragó, Miguel Ángel García-Quesada and Victoria Sánchez-Hellín

    Virology Journal 2017 14:97

    Published on: 25 May 2017

  2. Review

    Inhibitors compounds of the flavivirus replication process

    Flaviviruses are small viruses with single-stranded RNA, which include the yellow fever virus, dengue virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, and Zika virus; and are...

    Leidy L. García, Leonardo Padilla and Jhon C. Castaño

    Virology Journal 2017 14:95

    Published on: 15 May 2017

  3. Research

    Transcription profiles of the responses of chicken bursae of Fabricius to IBDV in different timing phases

    Infectious bursal disease virus (IBDV) infection causes immunosuppression in chickens and increases their susceptibility to secondary infections. To explore the interaction between host and IBDV, RNA-Seq was a...

    Changbo Ou, Qiuxia Wang, Yanhong Zhang, Weili Kong, Shouping Zhang, Yan Yu, Jinyou Ma, Xingyou Liu and Xianghui Kong

    Virology Journal 2017 14:93

    Published on: 10 May 2017

  4. Research

    Transplacental transmission of torque teno virus

    TTV has been detected in almost every human tissue type or body fluid reaching near 100% prevalence. Several studies report mother-to-child postnatal transmission of TTV in infancy but the risk of transplacent...

    Elena A. Tyschik, Sophia M. Shcherbakova, Ruslan R. Ibragimov and Denis V. Rebrikov

    Virology Journal 2017 14:92

    Published on: 8 May 2017

  5. Research

    Development of a simplified RT-PCR without RNA isolation for rapid detection of RNA viruses in a single small brown planthopper (Laodelphax striatellus Fallén)

    The small brown planthopper (SBPH) is an important pest of cereal crops and acts as a transmission vector for multiple RNA viruses. Rapid diagnosis of virus in the vector is crucial for efficient forecast and ...

    Qiufang Xu, Haoqiu Liu, Pingping Yuan, Xiaoxia Zhang, Qingqing Chen, Xuanli Jiang and Yijun Zhou

    Virology Journal 2017 14:90

    Published on: 3 May 2017

  6. Research

    Cucumber mosaic virus and its 2b protein alter emission of host volatile organic compounds but not aphid vector settling in tobacco

    Aphids, including the generalist herbivore Myzus persicae, transmit cucumber mosaic virus (CMV). CMV (strain Fny) infection affects M. persicae feeding behavior and performance on tobacco (Nicotiana tabacum), Ara...

    Trisna Tungadi, Simon C. Groen, Alex M. Murphy, Adrienne E. Pate, Javaid Iqbal, Toby J. A. Bruce, Nik J. Cunniffe and John P. Carr

    Virology Journal 2017 14:91

    Published on: 3 May 2017

  7. Review

    Hepatitis C virus management: potential impact of nanotechnology

    Around 170–200 million individuals have hepatitis C virus (HCV), which represents ~ 3% of the world population, including ~ 3–5 million people in the USA. According to the WHO regional office in the Middle Eas...

    Mostafa H. Elberry, Noureldien H. E. Darwish and Shaker A. Mousa

    Virology Journal 2017 14:88

    Published on: 2 May 2017

  8. Research

    Specific and quantitative detection of Human polyomaviruses BKPyV and JCPyV in the healthy Pakistani population

    The BK Polyomavirus (BKPyV) and JC polyomavirus (JCPyV) infections are widespread in human population and have been associated with severe kidney and brain disorders, respectively. The viruses remain latent pr...

    Iqra Hussain, Fareeda Tasneem, Muhammed Umer, Ayesha Pervaiz, Muslim Raza, Muhammad Imran Arshad and Naveed Shahzad

    Virology Journal 2017 14:86

    Published on: 24 April 2017

  9. Research

    Epidemiology and genotype distribution of human papillomavirus (HPV) in Southwest China: a cross-sectional five years study in non-vaccinated women

    Large-size data on type-specific HPV prevalence in Southwest China are required to estimate the cervical cancer burden in the country and to prepare for HPV-based cervical screening program and further HPV vac...

    Yishu Tang, Lan Zheng, Shuangshuang Yang, Bing Li, Huiting Su and Li-ping Zhang

    Virology Journal 2017 14:84

    Published on: 21 April 2017

  10. Research

    Unique LCR variations among lineages of HPV16, 18 and 45 isolates from women with normal cervical cytology in Ghana

    In addition to being useful for classification, sequence variations of human Papillomavirus (HPV) genotypes have been implicated in differential oncogenic potential and a differential association with the diff...

    Adolf K. Awua, Richard M. K. Adanu, Edwin K. Wiredu, Edwin A. Afari, Vanessa A. Zubuch, Richard H. Asmah and Alberto Severini

    Virology Journal 2017 14:85

    Published on: 21 April 2017

  11. Research

    A novel ViewRNA in situ hybridization method for the detection of the dynamic distribution of Classical Swine Fever Virus RNA in PK15 cells

    Classical swine fever (CSF) is a highly contagious fatal infectious disease caused by classical swine fever virus (CSFV). A better understanding of CSFV replication is important for the study of pathogenic mec...

    Qianyi Zhang, Lu Xu, Yujie Zhang, Tuanjie Wang, Xingqi Zou, Yuanyuan Zhu, Yan Zhao, Cui Li, Kai Chen, Yongfang Sun, Junxiang Sun, Qizu Zhao and Qin Wang

    Virology Journal 2017 14:81

    Published on: 18 April 2017

  12. Research

    Tissue tropisms, infection kinetics, histologic lesions, and antibody response of the MR766 strain of Zika virus in a murine model

    The appearance of severe Zika virus (ZIKV) disease in the most recent outbreak has prompted researchers to respond through the development of tools to quickly characterize transmission and pathology. We descri...

    Anna B. Kawiecki, E. Handly Mayton, M. Fausta Dutuze, Brad A. Goupil, Ingeborg M. Langohr, Fabio Del Piero and Rebecca C. Christofferson

    Virology Journal 2017 14:82

    Published on: 18 April 2017

  13. Review

    The role of nuclear localization signal in parvovirus life cycle

    Parvoviruses are small, non-enveloped viruses with an approximately 5.0 kb, single-stranded DNA genome. Usually, the parvovirus capsid gene contains one or more nuclear localization signals (NLSs), which are r...

    Peng Liu, Shun Chen, Mingshu Wang and Anchun Cheng

    Virology Journal 2017 14:80

    Published on: 14 April 2017

  14. Research

    Study of SV40 large T antigen nucleotide specificity for DNA unwinding

    Simian Virus 40 (SV40) Large Tumor Antigen (LT) is an essential enzyme that plays a vital role in viral DNA replication in mammalian cells. As a replicative helicase and initiator, LT assembles as a double-hex...

    Damian Wang, Ana Lucia Álvarez-Cabrera and Xiaojiang S. Chen

    Virology Journal 2017 14:79

    Published on: 14 April 2017

  15. Research

    Preliminary study of the UL55 gene based on infectious Chinese virulent duck enteritis virus bacterial artificial chromosome clone

    Lethal Duck Enteritis Virus (DEV) infection can cause high morbidity and mortality of many species of waterfowl within the order Anseriformes. However, little is known about the function of viral genes includi...

    Ying Wu, Yangguang Li, Mingshu Wang, Kunfeng Sun, Renyong Jia, Shun Chen, Dekang Zhu, Mafeng Liu, Qiao Yang, Xinxin Zhao, Xiaoyue Chen and Anchun Cheng

    Virology Journal 2017 14:78

    Published on: 13 April 2017

  16. Research

    Intranasal immunization of pigs with porcine reproductive and respiratory syndrome virus-like particles plus 2′, 3′-cGAMP VacciGrade™ adjuvant exacerbates viremia after virus challenge

    Porcine reproductive and respiratory syndrome virus (PRRSV) causes reproductive failure in pregnant sows and acute respiratory disease in young pigs. It is a leading infectious agent of swine respiratory compl...

    Alexandria Van Noort, April Nelsen, Angela E. Pillatzki, Diego G. Diel, Feng Li, Eric Nelson and Xiuqing Wang

    Virology Journal 2017 14:76

    Published on: 12 April 2017

  17. Research

    A guinea pig model of Zika virus infection

    Animal models are critical to understand disease and to develop countermeasures for the ongoing epidemic of Zika virus (ZIKV). Here we report that immunocompetent guinea pigs are susceptible to infection by a ...

    Mukesh Kumar, Keeton K. Krause, Francine Azouz, Eileen Nakano and Vivek R. Nerurkar

    Virology Journal 2017 14:75

    Published on: 11 April 2017

  18. Research

    Evaluation of the performance of Human Papillomavirus testing in paired urine and clinician-collected cervical samples among women aged over 30 years in Bhutan

    Urine sampling may offer a less invasive solution than cervical sampling to test for human papillomavirus (HPV) for HPV vaccine impact monitoring.

    Ugyen Tshomo, Silvia Franceschi, Tshokey Tshokey, Tashi Tobgay, Iacopo Baussano, Vanessa Tenet, Peter J. F. Snijders, Tarik Gheit, Massimo Tommasino, Alex Vorsters and Gary M. Clifford

    Virology Journal 2017 14:74

    Published on: 8 April 2017

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