Effect of S-region mutations on HBsAg in HBsAg-negative HBV-infected patients

Table 1 Effect of S-region mutation on HBsAg

	NC	Positive	G145R	T5A	G10D	F20S	T5A + G10D	T5A + F20S	G10D + F20S	T5A + G10D + F20S	S3N	I68T	I126T	S3N + I126T	S3N + I68T	I68T + I126T	S3N + I68T + I126T
24h	-	0.117	-	-	0.368	0.684	0.741	0.242	-	-	0.311	2.429	0.049	0.953	-	3.7	0.114
48h	-	0.988	-	0.029	4.097	1.508	3.688	0.666	-	-	1.275	6.75	0.455	1.259	0.037	15.819	0.958
72h	-	1.05	0.02	0.034	6.096	2.319	6.348	0.948	0.059	-	1.825	8.286	1.023	1.738	0.069	27.186	1.019
96h	-	0.88	0.019	0.027	6.903	1.833	6.499	0.857	0.059	-	1.641	7.834	0.872	1.279	0.061	27.743	0.854
120h	-	1.02	-	0.026	6.032	1.637	6.288	0.734	0.063	-	1.84	6.961	0.661	0.793	0.051	21.463	0.99
Cell lysate	-	0.947	-	0.021	4.58	1.357	4.595	0.616	0.712	0.013	0.867	3.947	0.475	1.686	0.045	7.393	0.919
HBV DNA (IU/mL)	-	1.22×10^7	3.14×10^7	4.41×10^5	1.14×10^6	1.24×10^5	3.91×10^5	2.14×10^6	2.73×10^6	1.08×10^7	7.14×10^4	4.76×10^6	4.36×10^4	1.55×10^7	3.66×10^6	1.55×10^6	1.94×10^5

ISSN: 1743-422X