Fig. 3

Changes of B cell and CD4⁺T cell subsets proportion of surface cytokines in vaccine group. Changes in the proportion of B cells, class switch B cells, plasma B cells, CD24⁺CD38^high Breg and CD24⁺CD27⁺ Breg in vaccine group at different time points (A). Changes in the proportion of CD4⁺T cells, Th1 cells, Th2 cells, Th17 cells and Tfh cells in vaccine group at different time points (B). The statistical analysis was determined by paired sample t-test