Fig. 2

The significant alterations in the expression of a large number of genes influenced by EBV in GC based on the TCGA data. (A) A Venn diagram depicting the shared genes is displayed, highlighting the overlap between the results of gene expression differences observed in the treatment group with EBV in the gastric cancer cell line and the comparison between EBV + and EBV- samples. (B) A collection of genes, chosen as candidate genes, are indicated to exhibit increased expression in GC but are capable of undergoing downregulation under the influence of EBV infection. (C) The enrichment results for the genes present in the heatmap of B section are demonstrated. (D) The heatmap corresponds to six genes that exhibited decreased expression in GC while could potentially undergo increased expression under the influence of EBV load. (E) The expression changes of six identified genes in the TCGA data, which show increased expression in both GC samples and could also be upregulated by EBV, are depicted. (F) The pathway enrichment results for the genes present in section E is demonstrated