Fig. 1

The Relationship Between EBV-induced gene expression changes and key malignancy pathways. (A) A volcano plot for all genes altered in a GC cell line due to EBV infection based on GSE185627 data is show. A fold change in expression greater than 1 or less than − 1, coupled with a FDR less than 0.05, was deemed as the cutoff criteri. (B) Enrichment results are shown for all genes that are increased due to EBV infection in GC cell lines. (C) Pathway results for genes that could be downregulated under the influence of EBV are highlighted. (D) The expression differences for all genes that exhibited changes in expression between EBV + and EBV- samples are depicted based on GSE51575. The cutoff criteria were defined as an expression fold change of larger than 1 or less than − 1 and an FDR < 0.05. (E) The pathways associated with upregulated genes in EBV + samples compared to EBV- samples are displayed. (F) The findings related to the enrichment of downregulated genes in EBV + samples compared to EBV- are presented