Fig. 1
From: Development of a highly sensitive and specific intact proviral DNA assay for HIV-1 subtype B and C
Comparison of the original and subtype B&C IPDA primer and probe subsets. A Overview of the target regions of the psi and env primers and probes. The original target sequences are indicated in green, the subtype B&C IPDA sequences in blue, overlapping sequences in yellow. Nucleotide positions relative to the HXB2 sequence are indicated. The two nucleotide changes in the hypermutated probe for env are underlined. B Frequency of homologous sequences within the Los Alamos compendium 2014, 2016 and 2020 for the original and the subtype B&C IPDA primers and probes